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Original scientific article

UTILIZING GENERATIVE AI CLINICAL PATIENT PERSONAS FOR ENHANCING DIAGNOSTIC ACCURACY AND THERAPEUTIC EMPATHY IN UNDERGRADUATE PSYCHOLOGY TRAINING

By
Mokhitabon Komilova Orcid logo ,
Mokhitabon Komilova
Contact Mokhitabon Komilova

Department of Uzbek and Foreign Languages, Fergana Medical Institute of Public Health , Fergana , Uzbekistan

Go‘yoxon Yakubova Orcid logo ,
Go‘yoxon Yakubova

Associate Professor, Fergana State University , Fergana , Uzbekistan

Shoxista Xolmurotova Orcid logo ,
Shoxista Xolmurotova

Lecturer, Department of Pedagogy and Psychology, Termez University of Economics and Service , Termez , Uzbekistan

Azizbek Mukhamedov Orcid logo ,
Azizbek Mukhamedov

Lecturer, Jizzakh State Pedagogical University , Jizzakh , Uzbekistan

Umida Djalilova Orcid logo ,
Umida Djalilova

Associate Professor, Department of Languages, Tashkent Institute of Chemical Technology , Tashkent , Uzbekistan

Aliya Kadirbaeva Orcid logo ,
Aliya Kadirbaeva

Associate Professor, Tashkent State Medical University , Tashkent , Uzbekistan

Bobur Juraev Orcid logo
Bobur Juraev

Bukhara State Medical Institute named after Abu Ali ibn Sino , Bukhara , Uzbekistan

Abstract

There is frequent conflict between diagnostic rigor and therapeutic empathy training in psychology undergraduates because students rarely encounter a variety of complex clinical presentations. This research investigates the usefulness of applying generative artificial intelligence (AI) clinical patient persona (GPT-4) by OpenAI to improve diagnostic accuracy and empathic interaction among psychology undergraduates. A quasi-experimental design was used, involving 124 third-year psychology students randomly assigned to either AI-persona training (n = 62) or traditional case-vignette training (n = 62) in a 6-week module. Structured simulated clinical interviews with dynamically responsive AI-generated personas simulating mood, anxiety, trauma-related, and personality disorders were provided to the intervention group. The measures were standardised using diagnostic accuracy rubrics and the Jefferson Scale of Empathy (JSE-S). Findings showed that students exposed to an AI persona had significantly better diagnostic accuracy (84.7% vs. 72.3%; p < .01) and better differentiation in diagnosis formulation (mean score change of 18.5; Cohen d = 0.74) than the controls. The JSE-S empathy scores increased by 21.2% in the intervention group compared with 8.9% in the control group (p < .01). Also, 89 % of the participants said they felt more confident in conducting clinical interviews, and 76 % said they felt more realistic than when using a static case study. The results indicate that clinical patient personas generated by generative AI can be a valuable addition to undergraduate psychology training, enhancing diagnostic competence and therapeutic empathy. A possible solution is to systematically incorporate simulated AI into training curricula, offering experience-based learning with scalable resource requirements at low cost, while maintaining ethical standards and pedagogical rigour.

References

1.
Chouhan S, Sandhu R, Channi HK, Ghai D, Singh G, Singh N. Revolutionizing Mental Healthcare with Generative Deep Learning Techniques for Enhanced Diagnosis and Treatment. InAdversarial Deep Generative Techniques for Early Diagnosis of Neurological Conditions and Mental Health Practises: Theoretical Insights with Practical Applications 2025 Jul 16 (pp. 347-372). Cham: Springer Nature Switzerland.
2.
Suárez-García RX, Chavez-Castañeda Q, Orrico-Pérez R, Valencia-Marin S, Castañeda-Ramírez AE, Quiñones-Lara E, Ramos-Cortés CA, Gaytán-Gómez AM, Cortés-Rodríguez J, Jarquín-Ramírez J, Aguilar-Marchand NG. DIALOGUE: A generative ai-based pre–post simulation study to enhance diagnostic communication in medical students through virtual type 2 diabetes scenarios. European Journal of Investigation in Health, Psychology and Education. 2025 Aug 7;15(8):152.
3.
Indrasary Y, Prihatmanto AS, Verasari M, Risnanto S, Frisca W, Yunautama D. Assessing Empathetic Engagement in AI-Generated Clinical Dialogues: A Computational-Psychological Hybrid Approach. In2025 19th International Conference on Telecommunication Systems, Services, and Applications (TSSA) 2025 Oct 30 (pp. 1-5). IEEE.
4.
Jia T, Pan F, Yang X, Ji L, Farina D, Li C. Artificial Empathy in Therapy and Healthcare: Advancements in Interpersonal Interaction Technologies. Cyborg and Bionic Systems. 2025 Dec 16;6:0473.
5.
Alastor E, Martínez-García I. Generative Artificial Intelligence in Medical-Humanistic Training: The Potential of Customised GPTs for Narrative Analysis. Medical Humanities & Medicina Narrativa-MHMN. 2025 Dec 9;12(3):53-72.

Citation

This is an open access article distributed under the  Creative Commons Attribution Non-Commercial License (CC BY-NC) License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 

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