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Original scientific article

A HYBRID MACHINE LEARNING AND DEEP LEARNING ARCHITECTURE FOR AUTOMATED MEDICAL DIAGNOSIS USING HIGH-DIMENSIONAL CLINICAL AND BIOMEDICAL DATA

By
Komal Saxena Orcid logo ,
Komal Saxena

Amity Institute of Information Technology, Amity University , Noida, Uttar Pradesh , India

M. Praneesh Orcid logo ,
M. Praneesh

Assistant Professor, Department of Computer Science with Data Analytics, Sri Ramakrishna College of Arts & Science , Coimbatore, Tamil Nadu , India

S. Nancy Lima Christy Orcid logo ,
S. Nancy Lima Christy

Assistant Professor, Department of Computer science and Engineering, SRM Institute of Science and Technology , Chennai, Tamil Nadu , India

K. Nandhini Orcid logo ,
K. Nandhini

Assistant Professor, Department of Computer Science and Engineering in Artificial Intelligence and Machine Learning, Sridevi Women's Engineering College , Hyderabad , India

Tolib Rajabov Orcid logo ,
Tolib Rajabov

Department of Medicine, Termez University of Economics and Service , Termez , Uzbekistan

M. Nalini Orcid logo ,
M. Nalini

Principal, Associate Professor of Mathematics, J.K.K Nataraja College of Arts & Science , Namakkal, Tamil Nadu , India

Shalu Gupta Orcid logo
Shalu Gupta

Associate Professor, Faculty of Computing, Guru Kashi University , Punjab , India

Abstract

The speed of the electronic healthcare system, clinical information system, and biomedical sensing technologies has resulted in the creation of extremely huge high-dimensional and heterogeneous medical data. Such data have substantial potential to automatically diagnose diseases, but are difficult to use because they are feature redundant, nonlinear, these models are often scalable and result in a limited interpretability of many existing models. Traditional machine learning (ML) techniques are based on manually designed features and do not always scale to high-dimensional inputs, whereas the deep learning (DL) ones, despite their mightiness, usually demand large annotated datasets and heavy computational resources. The proposed paper aims to suggest a hybrid architecture of ML and DL based on automated medical diagnosis on high-dimensional clinical and biomedical data, where deep learning based on representation learning is used together with effective classical classifiers. It consists of preprocessing (normalization, filling in of missing values, dimensionality reduction) and deep feature embedding with a hierarchical neural network and classification with optimized ML models. The proposed hybrid framework has an accuracy of 93.7, precision of 93.2, recall of 92.8, F1- score of 93.0 and AUC-ROC of 0.96, which is 3.4 to 7.3 percentage points better than standalone ML and DL models. These findings show that the hybrid design is better in diagnostic performance with less complexity of inference and scalability. The proposed system is thus seen to provide a viable and strong solution to smart e-health applications that aid in the credible automation of medical diagnosis and decision support in intelligent healthcare settings.

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Citation

This is an open access article distributed under the  Creative Commons Attribution Non-Commercial License (CC BY-NC) License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 

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